New painkiller: local and long-lasting relief

Loading player...
Pain relief after surgery is a major headache as we don't have a lot of effective, and safe, options. Opioids in particular, like morphine, are very addictive and cause hundreds of thousands of deaths globally each year, and so doctors are desperate for alternatives. Now, scientists at the University of Buffalo have developed a long-lasting, local painkiller that can be injected into the site of injury to specifically prevent pain-transmitting nerve cells, or neurons, from passing on their painful messages to the brain. It works by stopping a process called endocytosis; this is where cells... Like this podcast? Please help us by supporting the Naked Scientists
12 Oct 2021 English United Kingdom Science

Other recent episodes

Keeping humans healthy in orbit

With only a few walls between an astronaut and a rapid death, what do we know about the various dangers to the human body during space travel? Chris Smith spoke with Mark Shelhamer, a professor of Otolaryngology - Head and Neck Surgery at John Hopkins Medical School - about which…
10 Sep 6 min

Ants doing gene therapy, and tadpole microbiomes

This month, as the eLife Podcast hits its century, we hear how getting frog dads to cross-foster tadpoles has revealed the way in which some frogs come by their microbiomes, the ants that do gene therapy, signs that disease causes a breakdown in nutrient exchange between the elements of the…
7 Sep 43 min

Synthetic sustainable spuds

As the global population heads toward 10 billion, the pressure on agriculture is mounting. With that in mind, the UK's Advanced Research and Invention Agency (ARIA) has announced millions of pounds worth of funding for crops enhanced through synthetic biology by designing entirely new chromosomes and chloroplasts, starting with the…
9 Jul 5 min

Scientists say they've bent spacetime

"Warp speed, Mr Sulu." It's the kind of command we've only heard in science fiction - until now. Did a team of scientists just bend spacetime using nothing but sparks in a lab? That's right - not black holes, not neutron stars - electrical sparks. A new experiment claims to…
23 Jun 5 min

Finland's giant virus, and monkeys take care of their teeth

In the eLife podcast, a university compost heap has turned up Finland's first documented "giant virus". Also, why monkeys de-sand their supper, and how learning more languages actually makes brain tissue thinner. Then, the link between sugar and neonatal sepsis, and how a cancer controls its hydra host by bestowing…
19 Jun 38 min