CRISPR cuts life expectancy in twins

Loading player...
CRISPR stands for clustered regularly interspaced short palindromic repeats. Long name, but easy to picture: the sequence is synonymous to a word processor for a book, the book being DNA, which allows scientists to not only read the book, but to also edit a specific 'passage' of the book. Using CRISPR technology, DNA edits were performed on female twin embryos by Chinese scientist Jiankui He, who has since lost his standing in the scientific community. Xinzhu Wei Rasmus Nielsen, from the University of California Berkeley, followed up with the birth of the twins in an article published in the journal Nature Medicine and found a 21% increase in early mortality for the mutated genes. Matthew Hall visited Florian Merkle, a Senior Research Associate at the Institute of Metabolic Science right here in the University of Cambridge, to discuss the goal of He's experiment.
11 Jun 2019 English United Kingdom Science

Other recent episodes

Synthetic sustainable spuds

As the global population heads toward 10 billion, the pressure on agriculture is mounting. With that in mind, the UK's Advanced Research and Invention Agency (ARIA) has announced millions of pounds worth of funding for crops enhanced through synthetic biology by designing entirely new chromosomes and chloroplasts, starting with the…
9 Jul 5 min

Scientists say they've bent spacetime

"Warp speed, Mr Sulu." It's the kind of command we've only heard in science fiction - until now. Did a team of scientists just bend spacetime using nothing but sparks in a lab? That's right - not black holes, not neutron stars - electrical sparks. A new experiment claims to…
23 Jun 5 min

Finland's giant virus, and monkeys take care of their teeth

In the eLife podcast, a university compost heap has turned up Finland's first documented "giant virus". Also, why monkeys de-sand their supper, and how learning more languages actually makes brain tissue thinner. Then, the link between sugar and neonatal sepsis, and how a cancer controls its hydra host by bestowing…
19 Jun 38 min

Naked Scientists SOS

Cambridge University have informed us that, for cost cutting reasons, they intend to make Dr Chris Smith redundant. Naturally, this jeopardises the Naked Scientists programme, which is produced under his role. He will also lose his medical job. We regard this as a terrible decision and we intend to protest…
16 Jun 3 min

Insect extinctions, and AI shot in the arm for drug design

In episode 10 of the Cambridge Prisms Podcast, the shocking finding that as many as 2 invertebrate species are going extinct each week in Australia: what can be done? Also, the shot in the arm that AI is administering to the drug discovery industry, how do you measure the microplastic…
5 Jun 37 min